Troubleshooting Colloidal Gold Conjugate Stability

Why Does My Gold Turn Purple/Blue?

If your red colloidal gold turns purple or blue, it has aggregated (clumped). This kills assay performance. Causes include incorrect pH during conjugation or insufficient blocking.

Stabilization

Ensure your gold nanoparticles are capped with a high-quality stabilizer like BSA or PEG. Due Bio provides pre-conjugated Gold-Antibody solutions and high-stability bare gold specifically for LFA.

TL
Global Agent · Duebio (TiosBio) · 20+ Years in IVD
IVD industry veteran specializing in CRISPR Cas12/Cas13 detection, RAA isothermal amplification, lateral flow assays, microfluidic PCR, TRF immunoassays, and OEM/ODM IVD development for global distributors. Duebio is the international trade brand of TiosBio, a Chinese IVD manufacturer with 20+ years of experience.

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