False Negatives at Peak Infection
In acute phases (e.g., COVID-19 or CRP spikes), excess antigen can saturate antibodies, causing the Test line to fade. This “Hook Effect” is dangerous.
Three-Line Architecture
We recommend adding a third “Hook Line” or using Due Bio’s high-capacity sample pads to sequester excess antigen, extending the linear range of your assay.
TL
Global Agent · Duebio (TiosBio) · 20+ Years in IVD
IVD industry veteran specializing in CRISPR Cas12/Cas13 detection, RAA isothermal amplification, lateral flow assays, microfluidic PCR, TRF immunoassays, and OEM/ODM IVD development for global distributors. Duebio is the international trade brand of TiosBio, a Chinese IVD manufacturer with 20+ years of experience.