This product uses a chromatographic double-antibody sandwich method to simultaneously detect the target gene CRISPR digestion product and LAMP, RAA or RPA, PCR amplification product. This product can be used for detection when the CRISPR signal probe (A) or the amplification product (B) is modified as follows – one end of the CRISPR signal probe (A) is modified with biotin (Biotin), and the other end is modified with Fluorescein isothiocyanate (FITC) or 6-carboxyfluorescein (6-FAM); the amplification product (B) is modified with digoxin (Dig) at one end and rhodamine (TAMRA) at the other end.