Small Molecule Detection: Optimizing Competitive Assays for Pesticides

Competitive vs. Sandwich

Unlike COVID-19 (sandwich assay), detecting small molecules like Glyphosate or Antibiotics requires a Competitive Assay format. Here, the T-line intensity decreases as analyte concentration increases.

Critical Tuning

Competitive assays are highly sensitive to membrane flow rate. A slower wicking speed (e.g., 180s/4cm) is crucial to allow sufficient competition at the test line. Due Bio offers defined “Slow-Flow” strips specifically for this application.

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